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Kwashiorkor & Marasmus: Severe Malnutrition

Recognising and treating severe acute malnutrition in Nigerian children

Severe acute malnutrition (SAM) kills more than 450,000 Nigerian children under five annually โ€” making Nigeria one of the countries most affected globally. SAM presents as either kwashiorkor (protein deficiency with oedema), marasmus (severe wasting with no oedema), or marasmic-kwashiorkor (both). SAM is preventable and treatable โ€” but requires prompt recognition, referral, and appropriate nutritional rehabilitation.

Signs and Symptoms

โœ“ Kwashiorkor: swollen feet and legs (pitting oedema), pot belly, hair discolouration (reddish or grey), skin peeling, miserable and apathetic
โœ“ Marasmus: severe wasting โ€” can see ribs, shoulder blades, and hip bones; 'old man face'; folds of loose skin; alert and hungry despite extreme thinness
โœ“ Both: MUAC <11.5cm, weight-for-height Z-score <-3, or bilateral pitting oedema (even with normal weight = SAM)
โœ“ Complications: hypoglycaemia, hypothermia, severe infection โ€” any of these = immediate hospital admission

Risk Factors

When to Seek Help

Emergency hospitalisationAny child with SAM AND: bilateral oedema Grade 3 (up to groin/arms), any of the 'danger signs' (hypoglycaemia, severe dehydration, shock, altered consciousness, severe respiratory distress, high fever)
Community therapeutic care (CTC)Uncomplicated SAM (no medical complications) can be managed at home with Ready-to-Use Therapeutic Food (RUTF) and weekly clinic visits
ImmediatelyAny child with MUAC <11.5cm or visible severe wasting should be seen by a health worker the same day

Tests & Diagnosis

๐Ÿงช MUAC measurement
Mid-upper arm circumference: <11.5cm = severe acute malnutrition; 11.5โ€“12.5cm = moderate acute malnutrition
๐Ÿงช Bilateral pitting oedema check
Press thumbs on tops of both feet for 3 seconds โ€” if pitting (indentation) remains = kwashiorkor, classify as SAM regardless of weight
๐Ÿงช Blood glucose
All SAM children should have blood glucose checked: <3.0 mmol/L = hypoglycaemia, treat immediately with oral/IV glucose
๐Ÿงช Rapid malaria test (RDT)
Malaria commonly precipitates SAM decompensation; treat if positive
๐Ÿงช Weight and height/length
Plot on WHO growth charts; weight-for-height Z-score <-3 = SAM

Treatment Options

1
Phase 1: Stabilisation (first 1โ€“7 days in hospital)
F-75 therapeutic milk โ€” low protein formula to restore metabolism; treat infections, hypoglycaemia, hypothermia, and electrolyte imbalances; do NOT use standard high-protein milk
2
Transition phase (days 3โ€“7)
Gradual switch from F-75 to F-100 as oedema resolves and appetite returns
3
Phase 2: Rehabilitation (weeks 2โ€“6)
F-100 therapeutic milk or RUTF (Plumpy'Nut) โ€” high protein/calorie diet for rapid catch-up growth; may continue as outpatient
4
RUTF (Ready-to-Use Therapeutic Food)
Peanut-based paste with added vitamins and minerals โ€” provided free by UNICEF/government at CTC centres; given to child to eat directly from sachet
5
Micronutrient supplementation
Vitamin A (if deficient), zinc, folate โ€” given as part of standard SAM protocol
6
Follow-up
Weekly MUAC monitoring; immunisations once stabilised; family counselling on nutrition and feeding practices

Frequently Asked Questions

Is kwashiorkor caused only by protein deficiency?
It is primarily caused by protein deficiency and overall nutrient insufficiency. Modern evidence also implicates gut bacteria changes and aflatoxin exposure (from mouldy grains) in kwashiorkor development.
Where is RUTF available in Nigeria?
RUTF (Plumpy'Nut sachets) is distributed free through UNICEF-supported Outpatient Therapeutic Programmes (OTPs) at primary health centres in most states. Ask at your nearest health centre.
Can SAM children be treated at home?
Uncomplicated SAM (good appetite, no medical danger signs) is treated successfully at home with weekly RUTF supply and clinic follow-up. Complicated SAM requires hospital stabilisation first.
Why are SAM children given special milk โ€” not normal food?
In phase 1, normal food can worsen electrolyte imbalances and cause heart failure in severely malnourished children. F-75 is specially formulated with the right balance of nutrients for safe stabilisation.
How long does treatment take?
Hospital stabilisation takes 1โ€“2 weeks. RUTF outpatient rehabilitation takes 6โ€“8 weeks. Total recovery to normal growth can take 4โ€“6 months.

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