Stool Antigen · Blood Antibody · Rapid Urease · Lagos

H. Pylori & Ulcer Test in Lagos

Helicobacter pylori infection is the leading cause of peptic ulcers, chronic gastritis, and stomach cancer in Lagos. It is highly prevalent across Nigeria — yet simple, affordable testing makes it easy to detect and treat. Get accurate H. pylori testing in Lagos with results ready same day or next day.

~50%Lagos Prevalence
Same/24hResults
3 TestsAvailable
H. Pylori Panel
H. pylori Stool Ag Not detected Clear
H. pylori IgG Ab Negative Clear
Rapid Urease Negative Clear
FBC — Anaemia Screen Hb 13.4 g/dL Normal

Three H. Pylori Tests Available in Lagos

H. pylori infection is endemic in Lagos — estimated prevalence exceeds 50% in some adult populations. We offer three diagnostic approaches, ranging from the non-invasive stool antigen test (gold standard) to blood antibody serology and the rapid urease assay.

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Stool Antigen Test (HpSA)

The stool H. pylori antigen (HpSA) test is the non-invasive gold standard recommended by European and Lagos gastroenterology guidelines. It detects active H. pylori infection by identifying bacterial antigens shed into the stool — unlike the blood antibody test, it confirms current infection. It is also the preferred test of cure: repeat the stool antigen 4–8 weeks after completing eradication therapy to confirm successful treatment.

  • Detects active current infection
  • Sensitivity ~94%, specificity ~97%
  • Test of cure after eradication therapy
  • Stop PPIs and antibiotics 2 weeks before
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Blood Antibody Test (IgG Serology)

The H. pylori IgG antibody blood test detects exposure to H. pylori but cannot distinguish active current infection from past resolved infection — antibodies persist for years after eradication. This makes serology less useful as a test of cure, but it remains valuable for rapid screening in Lagos patients with dyspepsia who have never been tested. It requires no special preparation and gives same-day results.

  • Detects exposure — past or current
  • Same-day blood draw result
  • No preparation required
  • Not suitable as test of cure
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Rapid Urease Test

The rapid urease test (CLO test) exploits H. pylori's high urease activity — the enzyme it uses to survive the acidic stomach environment. A tissue sample or a stool specimen is incubated with urea; urease converts urea to ammonia, raising pH and producing a colour change. Results in 30–60 minutes. Highly specific (>95%) for active infection. Requires the same 2-week antibiotic/PPI washout as the stool antigen test.

  • Exploits H. pylori urease enzyme
  • Result in 30–60 minutes
  • High specificity (>95%)
  • Confirms active, current infection

Who Should Get an H. Pylori Test in Lagos?

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Chronic epigastric pain, burning, or bloating Burning or gnawing upper abdominal pain (especially after meals or at night), bloating, early satiety, or frequent belching in Lagos patients should prompt H. pylori testing before empirical PPI therapy — treat the cause, not just the symptoms.
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Upper GI bleed or iron-deficiency anaemia H. pylori-associated peptic ulcers bleed — presenting as haematemesis (vomiting blood), melaena (black tarry stool), or iron-deficiency anaemia without another cause. Test and eradicate H. pylori in all Lagos patients with unexplained iron deficiency.
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Before starting long-term NSAID or aspirin use H. pylori infection significantly increases the risk of peptic ulcer disease in Lagos patients who take NSAIDs (ibuprofen, diclofenac) or aspirin. Test and eradicate H. pylori before initiating long-term NSAID therapy to reduce ulcer risk by ~50%.
Test of cure after eradication therapy After completing triple or quadruple eradication therapy, a repeat H. pylori test (stool antigen or urea breath test) confirms that the infection was cleared. Without test of cure, ~20–30% of patients remain infected with resistant strains — leading to recurrent ulcers.
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Family history of H. pylori-related gastric cancer H. pylori is classified as a Class I carcinogen. Lagos patients with a first-degree family member who had gastric cancer or severe chronic atrophic gastritis should screen for H. pylori and eradicate if positive to reduce their risk.
H. Pylori Complications Untreated
Chronic gastritis Persistent H. pylori causes chronic inflammation of the gastric mucosa — early stage, common in Lagos patients with dyspepsia.
Peptic ulcer disease 80–85% of duodenal ulcers and 60–70% of gastric ulcers in Lagos are caused by H. pylori. Eradication cures most ulcers permanently.
Gastric MALT lymphoma Low-grade B-cell lymphoma of the gastric mucosa — H. pylori eradication induces remission in most early-stage cases.
Gastric adenocarcinoma H. pylori infection is the strongest modifiable risk factor for gastric cancer — a decades-long progression from gastritis to cancer.

Preparing for Your H. Pylori Test in Lagos

1

Stop Antibiotics & PPIs 2 Weeks Before

For the stool antigen test and rapid urease test: stop any antibiotics (amoxicillin, clarithromycin, metronidazole, tetracycline) and proton pump inhibitors (omeprazole, lansoprazole, pantoprazole) at least 14 days before testing. PPIs suppress H. pylori activity and significantly reduce sensitivity. H2-blockers (ranitidine, famotidine) should also be stopped 48 hours before testing if possible.

2

Stool Sample Collection

For the stool antigen test, bring a fresh stool specimen collected into a clean, dry container that morning. The sample should be pea-sized or larger. Do not use chemical toilet cleaners or contaminate the sample with urine or water. Refrigerate (not freeze) if you cannot bring it within 2–3 hours. Our Lagos laboratory accepts same-morning specimens.

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Blood Antibody Test — No Preparation Needed

The H. pylori IgG blood antibody test requires no fasting, no medication changes, and no special preparation. A simple blood draw provides same-day results. Remember that a positive blood antibody result indicates past or current exposure — it does not confirm active infection, and it cannot be used to confirm eradication. Use the stool antigen test for those purposes.

Lagos's H. Pylori Testing Centre

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Three validated test methods

We offer stool antigen test, blood antibody (IgG serology), and rapid urease assay — so the right test is chosen for your clinical situation. Test of cure? Stool antigen. Rapid screening? Serology. Confirmation of active infection? Rapid urease or stool antigen.

Same-day or next-day Lagos results

Blood antibody results are available the same day. Stool antigen results are available within 24–48 hours. We advise on eradication regimens (triple or bismuth-based quadruple therapy) available in Lagos, so you leave with a clear action plan.

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Expert interpretation — not just a result slip

A positive H. pylori result is the beginning, not the end. We explain what your result means, which Lagos eradication regimen is appropriate, and when to return for a test of cure. Lagos patients with resistant H. pylori or recurrent symptoms are guided on further investigation.

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Accessible from all Lagos areas

52 Sholanke Street, Akoka — central to the Lagos Mainland and easily reached from Lagos Island and Lekki. Open Mon – Sat, 9 AM – 5 PM. WhatsApp booking for minimal waiting time.

"I had been having stomach pain for months and was just taking omeprazole from the pharmacy. Came to Mascot for the H. pylori stool test — came back positive. After completing triple therapy, I retested and it was clear. The pain is completely gone. Finally an actual diagnosis."

OA
O.A.Yaba, Lagos
✓ Stool antigen — gold standard
✓ Same-day blood antibody result
✓ Test of cure service included
Book Your H. Pylori Test in Lagos

Stomach Ulcer Testing — Fast & Accurate in Lagos

Walk in or book ahead. Located at 52 Sholanke Street, Off Chemist Junction, Akoka, Lagos.

Monday – Saturday  ·  9:00 AM – 5:00 PM  ·  Closed Sundays & Public Holidays

Stop antibiotics 2 weeks before  ·  Stool or blood sample  ·  Walk-ins welcome Mon – Sat