ALT · AST · ALP · GGT · Bilirubin · Lagos

Liver Function Test in Lagos

Seven liver markers from a single fasted blood draw — enzymes, bilirubin, and protein synthesis indicators. Given Lagos's high hepatitis B burden and widespread fatty liver disease, routine LFT is one of the most important annual health checks for Lagos adults.

7Markers Measured
8hFast Required
SameDay Results
Liver Function Panel
ALT 87 U/L Elevated
AST 54 U/L Elevated
ALP 112 U/L Normal
Total Bilirubin 18 µmol/L Normal
Albumin 38 g/L Normal

Three Liver Domains, One Panel

The LFT panel assesses liver damage (enzymes), bile processing (bilirubin), and synthetic function (albumin). Together they tell whether the liver is inflamed, obstructed, or failing.

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Liver Enzymes

ALT (alanine aminotransferase) is the most liver-specific enzyme — elevated ALT is the hallmark of hepatocellular damage from HBV, fatty liver, and drug injury. AST rises in both liver and muscle damage. ALP and GGT elevation suggests bile duct obstruction or alcohol-related liver disease — common in Lagos adults.

  • ALT/AST normal: <40 U/L
  • ALT >3× ULN: significant hepatocellular injury
  • ALP normal: 40–130 U/L
  • GGT >55 U/L: alcohol, drugs, biliary
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Bilirubin (Total, Direct, Indirect)

Bilirubin is a breakdown product of haemoglobin. Elevated bilirubin causes jaundice — yellowing of skin and sclera (eyes). Direct (conjugated) bilirubin rises in bile duct obstruction and hepatitis; indirect rises in haemolytic conditions. Total bilirubin <21 µmol/L is normal.

  • Total bilirubin: <21 µmol/L normal
  • Elevated direct: hepatitis, bile obstruction
  • Elevated indirect: haemolysis, Gilbert's syndrome
  • Clinical jaundice visible at >34 µmol/L
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Albumin & Total Protein

Albumin is produced exclusively by the liver — low albumin (hypoalbuminaemia) indicates impaired liver synthetic function, seen in cirrhosis, malnutrition, or nephrotic syndrome. It is the most sensitive indicator of chronic liver failure. Total protein includes albumin plus globulins — elevated globulins may suggest chronic infection or inflammation.

  • Albumin: 35–50 g/L normal
  • <25 g/L: severe hypoalbuminaemia
  • Total protein: 60–80 g/L normal
  • Low albumin = chronic liver failure marker

Who Needs an LFT in Lagos?

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Known hepatitis B or C in Lagos HBsAg-positive Lagos patients require annual LFT to monitor liver inflammation, guide antiviral treatment decisions, and detect early cirrhosis before liver cancer develops.
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Jaundice (yellow eyes or skin) Any Lagos patient presenting with jaundice needs an urgent LFT to determine the cause — hepatitis, biliary obstruction, drug toxicity, or haemolysis — each requiring a different management pathway.
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Alcohol use or fatty liver Alcohol-related liver disease and non-alcoholic fatty liver disease (NAFLD) are increasingly common in Lagos. GGT is an early marker of alcohol damage; ALT elevation signals hepatocellular fat infiltration.
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Lagos patients on long-term medications Statins, antituberculosis drugs, antiretrovirals, and many Lagos herbal concoctions are hepatotoxic. Baseline and monitoring LFTs are essential for these patients.
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Right upper abdominal pain Pain in the right upper quadrant — common in Lagos patients with gallstones, hepatitis, or liver abscess — requires LFT as the first-line investigation alongside an ultrasound request.
Normal Reference Ranges
ALT (Alanine Aminotransferase) Normal: <40 U/L  |  >120 U/L: significant hepatocellular injury
AST (Aspartate Aminotransferase) Normal: <40 U/L  |  AST > ALT suggests alcoholic hepatitis
GGT (Gamma-glutamyl transferase) Men: <55 U/L  |  Women: <38 U/L  |  Sensitive alcohol marker
Total Bilirubin Normal: <21 µmol/L  |  >34 µmol/L: clinical jaundice
Albumin Normal: 35–50 g/L  |  <30 g/L: impaired liver synthesis

Prepare for an Accurate Liver Test

1

8-Hour Overnight Fast

Fast for 8 hours before your LFT. Fatty meals raise triglycerides and ALP non-specifically, obscuring hepatobiliary pathology. Lagos patients scheduling early morning tests from Lekki or Lagos Island should avoid breakfast en route. Water is permitted throughout the fast.

2

Avoid Alcohol for 24 Hours

Alcohol is directly hepatotoxic and transiently raises GGT, ALT, and AST. Avoid all alcohol for at least 24 hours before your test — ideally 48 hours for regular drinkers. This ensures your LFT result reflects true liver status, not acute alcohol effect.

3

List All Medications

Bring a complete medication and supplement list — statins (atorvastatin, rosuvastatin), anti-TB drugs (rifampicin, isoniazid), antiretrovirals, paracetamol (at high doses), and Lagos herbal preparations all affect liver enzymes. Do not stop medications without medical guidance — we need to see results on your current regimen.

Lagos's Liver Testing Centre

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7-marker LFT panel including GGT

Many Lagos laboratories omit GGT from their LFT. We include ALT, AST, ALP, GGT, total bilirubin, direct bilirubin, and albumin — the complete panel for meaningful liver assessment.

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Results with clinical interpretation

Your report identifies the pattern of enzyme abnormality — hepatocellular (ALT/AST dominant) vs. cholestatic (ALP/GGT dominant) — guiding next steps for Lagos clinicians without delay.

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Longitudinal monitoring for Lagos HBV patients

Chronic HBV patients in Lagos need serial LFT to track liver inflammation trends. We retain records across visits — enabling meaningful comparison between quarterly results.

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Accessible from all Lagos areas

52 Sholanke Street, Akoka — convenient for Yaba, Shomolu, Lagos Island, and Lekki. Open Mon – Sat 9 AM – 5 PM. WhatsApp booking recommended for fasted morning slots.

"My HBV doctor in Lagos kept prescribing tenofovir without monitoring my LFT. Mascot ran the full panel and found my ALT was 6× upper normal — my dose needed adjusting. Grateful for their thoroughness."

JO
J.O.Lagos Island
✓ Full 7-marker LFT including GGT
✓ Same-day Lagos results
✓ Hepatobiliary pattern interpretation
Book Your Liver Function Test in Lagos

Protect Your Liver — Test Now

Walk in or book ahead. Located at 52 Sholanke Street, Off Chemist Junction, Akoka, Lagos.

Monday – Saturday  ·  9:00 AM – 5:00 PM  ·  Closed Sundays & Public Holidays

8-hour fast required  ·  7 markers measured  ·  Same-day results  ·  Walk-ins welcome Mon – Sat