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Preeclampsia Warning Signs

A dangerous pregnancy complication โ€” recognise it before it becomes eclampsia

Preeclampsia is a pregnancy complication characterised by high blood pressure (โ‰ฅ 140/90 mmHg) and signs of organ damage โ€” most commonly protein in the urine โ€” after 20 weeks of pregnancy. It affects 2โ€“8% of pregnancies globally and is a leading cause of maternal and perinatal death in Nigeria. Without treatment, preeclampsia can progress to eclampsia (seizures), stroke, organ failure, and death. The only cure is delivery of the baby and placenta. Early detection at antenatal visits and prompt action saves lives.

Signs and Symptoms

โœ“ High blood pressure: โ‰ฅ 140/90 mmHg on two readings 4 hours apart
โœ“ Severe headache that does not respond to paracetamol
โœ“ Visual disturbances: blurred vision, flashing lights, seeing spots
โœ“ Swelling (oedema) of the face, hands, and ankles (sudden or severe)
โœ“ Pain in the upper right abdomen or epigastric (stomach) pain
โœ“ Nausea and vomiting after 20 weeks (new onset)
โœ“ Shortness of breath (fluid on lungs โ€” pulmonary oedema)
โœ“ Reduced urine output or dark coloured urine
โœ“ Sudden weight gain of more than 1kg per week (fluid retention)

Risk Factors

When to Seek Help

EMERGENCY โ€” call for help immediatelySeizures (eclampsia), loss of consciousness, inability to see, or severe chest pain require emergency care NOW
Same-day hospital attendanceSevere headache + high BP, vision changes, right upper abdominal pain, or sudden severe oedema โ€” do not wait for next ANC visit
Blood pressure โ‰ฅ 160/110 mmHg at homeSevere hypertension in pregnancy requires urgent IV treatment to prevent stroke
Reduced fetal movement with any preeclampsia symptomBaby may be compromised โ€” needs immediate CTG (cardiotocography) monitoring
Any preeclampsia symptom before 34 weeksPreterm preeclampsia has highest complication rates โ€” specialist management required

Tests & Diagnosis

๐Ÿงช Blood pressure monitoring
At every ANC visit โ€” the most important screening tool. Home BP monitoring recommended for high-risk women
๐Ÿงช Urine dipstick for protein
โ‰ฅ 2+ protein on dipstick triggers formal 24-hour urine protein collection or PCR/ACR ratio
๐Ÿงช Full blood count
Thrombocytopaenia (low platelets < 100,000) is a sign of HELLP syndrome โ€” a severe preeclampsia variant
๐Ÿงช Liver function tests
Raised AST/ALT indicates liver involvement in HELLP syndrome
๐Ÿงช Kidney function tests
Rising creatinine shows kidney involvement and worsening severity
๐Ÿงช Uric acid
Raised uric acid correlates with severity and fetal compromise
๐Ÿงช Fetal ultrasound and Doppler
Assesses fetal growth restriction and umbilical artery blood flow โ€” fetal compromise requires earlier delivery
๐Ÿงช PlGF (placental growth factor)
A newer blood test that can help confirm or rule out preeclampsia โ€” becoming available in some Nigerian tertiary hospitals

Treatment Options

1
Antihypertensive drugs
Labetalol, methyldopa, or nifedipine are safe in pregnancy. IV labetalol or hydralazine for severe hypertension (โ‰ฅ 160/110)
2
Magnesium sulphate
The most important drug โ€” prevents and treats eclamptic seizures. Given IV or IM in hospital. Life-saving and widely available
3
Low-dose aspirin (prevention)
75โ€“150mg daily from 12โ€“16 weeks for high-risk women reduces preeclampsia risk by 10โ€“20%
4
Calcium supplementation
1.5g/day in women with low dietary calcium intake reduces preeclampsia by about 50%
5
Delivery
The only cure. Timing depends on severity and gestational age. Mild preeclampsia: deliver by 37 weeks. Severe: often earlier
6
Corticosteroids (if preterm)
Betamethasone or dexamethasone given to accelerate fetal lung maturity if delivery before 34 weeks likely

Frequently Asked Questions

Can preeclampsia happen without symptoms?
Yes โ€” that is why blood pressure is checked at every ANC visit. Many women feel well despite having dangerously high blood pressure. Never skip ANC visits assuming you feel fine.
Will preeclampsia come back in my next pregnancy?
If you had severe or early-onset preeclampsia, your risk in the next pregnancy is 15โ€“25%. Starting low-dose aspirin from 12 weeks and ensuring BP is well-controlled before conception reduces this risk significantly.
Is preeclampsia the same as eclampsia?
No. Preeclampsia is the hypertensive disorder with organ involvement. Eclampsia is preeclampsia that has progressed to seizures โ€” a medical emergency with much higher death rates. Magnesium sulphate both prevents and treats eclampsia.
Can I deliver at home if I have preeclampsia?
Absolutely not. Preeclampsia and eclampsia require hospital management, IV medications, continuous monitoring, and rapid access to caesarean section. Home delivery with preeclampsia is extremely dangerous for both mother and baby.

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