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Food Allergies (Nigeria Guide)

Immune reactions to food — symptoms, trigger foods in Nigeria, and emergency management

Food allergy is an immune-mediated reaction to food proteins that causes symptoms ranging from mild hives to life-threatening anaphylaxis. It affects approximately 2–5% of adults and 6–8% of children globally. In Nigeria, the most clinically relevant food allergens differ from the Western 'Big 9' — groundnuts (peanuts), fish, shellfish, soya, egg, and milk are all significant. Food intolerance (non-immune reactions, such as lactose intolerance) is often confused with food allergy — the distinction matters for diagnosis and management.

Signs and Symptoms

✓ Skin reactions (most common) — urticaria (hives), angioedema (swelling of face, lips, tongue), eczema flare
✓ Oral allergy syndrome — itching and tingling of the mouth, lips, and throat immediately after eating
✓ Gastrointestinal — nausea, vomiting, abdominal cramps, diarrhoea within 2 hours of eating
✓ Respiratory — sneezing, runny nose, wheeze, or difficulty breathing
✓ Anaphylaxis — sudden collapse, throat closure, difficulty breathing, low blood pressure — life-threatening
✓ Delayed reactions (non-IgE mediated) — GI symptoms hours after eating (FPIES, eosinophilic oesophagitis)

Risk Factors

When to Seek Help

Emergency — call 112 or go immediatelyThroat tightening, difficulty swallowing, voice change, wheeze, dizziness, or collapse after eating — ANAPHYLAXIS. Give adrenaline (epinephrine) if available, call for help
Same dayUrticaria (hives) spreading rapidly over large body areas, swelling of lips or tongue
SoonSuspected food allergy — diagnostic testing needed before dietary elimination
RoutineRecurrent unexplained urticaria or GI symptoms — food allergy or other cause investigation
Paediatric allergy referralChild with eczema and suspected food allergy — early assessment and introduction guidance

Tests & Diagnosis

🧪 Skin prick test
With commercial or fresh food extracts — positive wheal (≥3 mm greater than negative control) supports IgE-mediated allergy. Available at allergy clinics
🧪 Serum specific IgE (food panels)
Blood test — measures IgE to specific foods (peanut, milk, egg, fish, soya, wheat panels). A positive result means sensitisation — not always clinical allergy
🧪 Oral food challenge (OFC)
Gold standard for diagnosis — supervised ingestion of increasing amounts of the suspected food. Performed in a clinical setting with emergency resuscitation available. Confirms or excludes clinical allergy
🧪 Elimination diet trial
Remove suspected food for 4–6 weeks, then reintroduce under medical supervision — used for suspected non-IgE-mediated allergy where skin testing is negative
🧪 Atopy patch test
For delayed GI and skin reactions (FPIES, eosinophilic conditions) — not routine

Treatment Options

1
Strict avoidance of the identified allergen
Read ingredient labels carefully. Nigerian processed foods increasingly include allergen labelling. Beware of cross-contamination in food preparation. Inform restaurants and food vendors of your allergy
2
Emergency adrenaline (epinephrine) auto-injector
All patients with a history of anaphylaxis must carry an adrenaline auto-injector (Epipen or equivalent). Available at major Nigerian pharmacies and LUTH/UCH immunology clinics. Two pens should be carried at all times. Train the patient and family to use it
3
Antihistamines for mild reactions
Cetirizine or loratadine for mild urticaria. Chlorphenamine for more rapid effect (sedating). Antihistamines are NOT effective for anaphylaxis — adrenaline is the only life-saving treatment
4
Oral allergy syndrome
Usually managed by avoiding the raw food — cooking destroys the proteins causing oral allergy. Most people with oral allergy syndrome can tolerate cooked versions of the triggering food
5
Lactose intolerance vs milk allergy
Lactose intolerance (very common in Nigeria — most adult Nigerians lack lactase) causes bloating, gas, and diarrhoea — but no hives, swelling, or anaphylaxis. Treatment: lactase enzyme supplements or low-lactose products. Milk protein allergy (IgE-mediated) causes immune reactions — strict avoidance needed
6
Food allergy in children — early introduction
Contrary to old advice, early introduction of allergenic foods (from 4–6 months) PREVENTS allergy development. Children with eczema should have early introduction under medical guidance. LEAP study evidence: early peanut introduction reduces peanut allergy by 80%
7
Immunotherapy for food allergy (oral immunotherapy — OIT)
Gradually increasing doses of the allergen to induce tolerance. Primarily for peanut (approved: Palforzia). Not yet widely available in Nigeria. Can be life-changing for children with severe peanut allergy

Frequently Asked Questions

Is groundnut (peanut) allergy common in Nigeria?
Yes — though rates are lower than in Western countries (possibly due to early introduction in Nigerian diets from infancy). Peanut allergy is the most common cause of fatal anaphylaxis in children worldwide. Nigerian children who have not been regularly eating groundnuts should not be given them for the first time without medical guidance if they have eczema or other allergies.
Can you develop a food allergy as an adult?
Yes. New food allergies can develop at any age. Shellfish allergy commonly develops in adults who have eaten shellfish for years. Wheat allergy can develop in bakers (occupational allergy). Any new unexplained reaction after eating a food warrants allergy evaluation.
Is food intolerance the same as food allergy?
No. Food allergy involves the immune system — even tiny amounts can cause severe reactions including anaphylaxis. Food intolerance (e.g., lactose intolerance, histamine intolerance) causes discomfort but is not immune-mediated and is not life-threatening. The distinction matters for severity of avoidance and need for adrenaline.
What should I do if I accidentally eat a food I'm allergic to?
Mild symptoms (hives, itching): take an antihistamine and observe closely. Throat tightening, difficulty breathing, voice change, dizziness, or feeling faint: use adrenaline auto-injector immediately if available, then call for emergency help. Always go to hospital after using adrenaline — biphasic reactions (second wave of anaphylaxis) can occur up to 8 hours later.

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