{"id":3210,"date":"2026-10-28T19:10:56","date_gmt":"2026-10-28T18:10:56","guid":{"rendered":"https:\/\/mascothealthcare.com\/blog\/?p=3210"},"modified":"2026-10-28T19:11:01","modified_gmt":"2026-10-28T18:11:01","slug":"as-and-as-couples-options-before-pregnancy","status":"publish","type":"post","link":"https:\/\/mascothealthcare.com\/blog\/as-and-as-couples-options-before-pregnancy\/","title":{"rendered":"AS and AS Couples: Your Options Before and During Pregnancy"},"content":{"rendered":"\n

Quick answer:<\/strong> When both partners are AS, each pregnancy has a 1 in 4 chance of a child with sickle cell disease (SS), a 1 in 2 chance of a child who is AS, and a 1 in 4 chance of a child who is AA. These chances are the same for every pregnancy. Couples have real options, and the right choice is a personal one, best made with good information.<\/p>\n\n\n\n

First, confirm both genotypes<\/h2>\n\n\n\n

Make sure both results are reliable. If you’ve had two results that disagree, or a blood transfusion in the last 3 months, repeat the test. See our genotype test<\/a>.<\/p>\n\n\n\n

Your chances with each pregnancy<\/h2>\n\n\n\n
Child’s genotype<\/th>Chance in each pregnancy<\/th><\/tr><\/thead>
AA<\/td>1 in 4<\/td><\/tr>
AS (carrier, healthy)<\/td>1 in 2<\/td><\/tr>
SS (sickle cell disease)<\/td>1 in 4<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

“1 in 4” doesn’t mean one child in every four. Every pregnancy is a fresh 1 in 4 chance.<\/p>\n\n\n\n

The options couples consider<\/h2>\n\n\n\n